Photo by Amber Palmer
Holiday rentals near Mayo Clinic Florida
We found 1,346 holiday rentals — enter your dates for availability
Discover a selection of holiday rentals within easy reach of Mayo Clinic Florida that can be your home away from home. Whether you’re travelling with friends, family or just with your pet, holiday homes have the best amenities for hanging out with the people that matter most, which might include parking and a fireplace. No matter what you're looking for, you're sure to find a property to rent that has what everyone needs, including accessible or non-smoking choices.
Holiday rentals with weekly discounts - Mayo Clinic Florida
Showing deals for:15 Aug - 22 Aug
Image gallery for Gated SAWGRASS BEACH CLUB - WALK to BEACH!
1010 out of 10 rating
Exceptional
(31 reviews)
Gated SAWGRASS BEACH CLUB - WALK to BEACH!
Ponte Vedra Beach, FL
8% off
Price is NZ$3,087
NZ$3,087
NZ$441 per night
includes taxes & fees
Image gallery for Beachy Cottage by the sea
1010 out of 10 rating
Exceptional
(81 reviews)
Beachy Cottage by the sea
Jacksonville Beach, FL
8% off
Price is NZ$4,539
NZ$4,539
NZ$648 per night
includes taxes & fees
Image gallery for Lux Italian house close to the beach
9.69.6 out of 10 rating
Exceptional
(10 reviews)
Lux Italian house close to the beach
Jacksonville, FL
8% off
Price is NZ$5,187
NZ$5,187
NZ$741 per night
includes taxes & fees
Image gallery for Octopi the Beach - Luxury oceanside home 10 min to Mayo and pet friendly
1010 out of 10 rating
Exceptional
(19 reviews)
Octopi the Beach - Luxury oceanside home 10 min to Mayo and pet friendly
Jacksonville Beach, FL
12% off
Price is NZ$4,878
NZ$4,878
NZ$697 per night
includes taxes & fees
Image gallery for Beach Escape – 2.5 Blocks to Ocean, Fenced Yard, Split Plan & Outdoor Living!
1010 out of 10 rating
Exceptional
(26 reviews)
Beach Escape – 2.5 Blocks to Ocean, Fenced Yard, Split Plan & Outdoor Living!
Jacksonville Beach, FL
7% off
Price is NZ$2,435
NZ$2,435
NZ$348 per night
includes taxes & fees
Image gallery for TPC Sawgrass Coastal Getaway - Hot tub, golf, beach, pickle ball, Mayo Clinic
1010 out of 10 rating
Exceptional
(17 reviews)
TPC Sawgrass Coastal Getaway - Hot tub, golf, beach, pickle ball, Mayo Clinic
Ponte Vedra Beach, FL
8% off
Price is NZ$4,308
NZ$4,308
NZ$615 per night
includes taxes & fees
Image gallery for Water Front * Deep Water Dock * Fishing * Spectacular Views * RV Experience
1010 out of 10 rating
Exceptional
(80 reviews)
Water Front * Deep Water Dock * Fishing * Spectacular Views * RV Experience
Jacksonville, FL
8% off
Price is NZ$1,451
NZ$1,451
NZ$207 per night
includes taxes & fees
Image gallery for Luxe Villa by Ocean w/ Bikes + Game Room Paradise
1010 out of 10 rating
Exceptional
(5 reviews)
Luxe Villa by Ocean w/ Bikes + Game Room Paradise
Jacksonville Beach, FL
11% off
Price is NZ$5,361
NZ$5,361
NZ$766 per night
includes taxes & fees
Image gallery for Beach & pool in South Jax Beach sleeps 8 to 12!
9.69.6 out of 10 rating
Exceptional
(22 reviews)
Beach & pool in South Jax Beach sleeps 8 to 12!
Jacksonville Beach, FL
6% off
Price is NZ$9,031
NZ$9,031
NZ$1,290 per night
includes taxes & fees
Image gallery for Jax Beach House w/Pool and Outdoor Oasis
1010 out of 10 rating
Exceptional
(28 reviews)
Jax Beach House w/Pool and Outdoor Oasis
Jacksonville Beach, FL
8% off
Price is NZ$5,566
NZ$5,566
NZ$795 per night
includes taxes & fees
Image gallery for Renovated & Beautifully Decorated Jax Beach Home
1010 out of 10 rating
Exceptional
(14 reviews)
Renovated & Beautifully Decorated Jax Beach Home
Jacksonville Beach, FL
8% off
Price is NZ$2,888
NZ$2,888
NZ$413 per night
includes taxes & fees
Image gallery for Four-bedroom mini estate, minutes from downtown Jax with a sunroom and backyard
9.49.4 out of 10 rating
Exceptional
(9 reviews)
Four-bedroom mini estate, minutes from downtown Jax with a sunroom and backyard
Jacksonville, FL
7% off
Price is NZ$2,515
NZ$2,515
NZ$359 per night
includes taxes & fees
Image gallery for Beach Retreat Complex w/Pool - Sleeps 25!
1010 out of 10 rating
Exceptional
(5 reviews)
Beach Retreat Complex w/Pool - Sleeps 25!
Jacksonville Beach, Florida
8% off
Price is NZ$22,163
NZ$22,163
NZ$3,166 per night
includes taxes & fees
Image gallery for Walk Everywhere ★ Spacious, Amazing, Clean Retreat ★ Luxury Beach Townhome
9.89.8 out of 10 rating
Exceptional
(6 reviews)
Walk Everywhere ★ Spacious, Amazing, Clean Retreat ★ Luxury Beach Townhome
Jacksonville Beach, FL
7% off
Price is NZ$3,375
NZ$3,375
NZ$482 per night
includes taxes & fees
Image gallery for 4 blocks from beach! spacious getaway w game room, outdoor kitchen. Kid-friendly
1010 out of 10 rating
Exceptional
(14 reviews)
4 blocks from beach! spacious getaway w game room, outdoor kitchen. Kid-friendly
Jacksonville Beach, FL
11% off
Price is NZ$5,449
NZ$5,449
NZ$778 per night
includes taxes & fees
Image gallery for Beautiful Beach House, Heated Pool+Backyard Oasis
1010 out of 10 rating
Exceptional
(48 reviews)
Beautiful Beach House, Heated Pool+Backyard Oasis
Jacksonville Beach, FL
9% off
Price is NZ$4,941
NZ$4,941
NZ$706 per night
includes taxes & fees
Image gallery for Jax Vacations 1/2 Mile to Beach, 2 bedroom, pet friendly, close to Mayo Clinic
9.89.8 out of 10 rating
Exceptional
(16 reviews)
Jax Vacations 1/2 Mile to Beach, 2 bedroom, pet friendly, close to Mayo Clinic
Jacksonville Beach, FL
7% off
Price is NZ$2,213
NZ$2,213
NZ$316 per night
includes taxes & fees
Image gallery for Mayo Clinc 1mile from Intercoastal waterfront home w/pool and Breathtaking Views
9.89.8 out of 10 rating
Exceptional
(106 reviews)
Mayo Clinc 1mile from Intercoastal waterfront home w/pool and Breathtaking Views
Jacksonville Beach, FL
9% off
Price is NZ$4,486
NZ$4,486
NZ$641 per night
includes taxes & fees
Image gallery for Location! Location! Beach House 100 yards from ocean!
1010 out of 10 rating
Exceptional
(158 reviews)
Location! Location! Beach House 100 yards from ocean!
Jacksonville Beach, FL
8% off
Price is NZ$3,318
NZ$3,318
NZ$474 per night
includes taxes & fees
Image gallery for Beautiful 2 bedroom condo steps to the Beach & Pool
1010 out of 10 rating
Exceptional
(5 reviews)
Beautiful 2 bedroom condo steps to the Beach & Pool
Jacksonville Beach, FL
8% off
Price is NZ$4,121
NZ$4,121
NZ$589 per night
includes taxes & fees
Image gallery for Location! Location! Location! BEACH, Shopping, Park, All 3 min walk! Super Clean
1010 out of 10 rating
Exceptional
(8 reviews)
Location! Location! Location! BEACH, Shopping, Park, All 3 min walk! Super Clean
Jacksonville Beach, FL
8% off
Price is NZ$4,851
NZ$4,851
NZ$693 per night
includes taxes & fees
Image gallery for Waterfront Cottage * Deep Water Dock * Fishing * Spectacular Sunrises
9.89.8 out of 10 rating
Exceptional
(72 reviews)
Waterfront Cottage * Deep Water Dock * Fishing * Spectacular Sunrises
Jacksonville, FL
8% off
Price is NZ$1,896
NZ$1,896
NZ$271 per night
includes taxes & fees
Image gallery for Walk To Beach!Near JTB, Mayport, MayoClinic, TPC+Sawgrass! Large fenced yard!
1010 out of 10 rating
Exceptional
(47 reviews)
Walk To Beach!Near JTB, Mayport, MayoClinic, TPC+Sawgrass! Large fenced yard!
Jacksonville Beach, FL
12% off
Price is NZ$4,838
NZ$4,838
NZ$691 per night
includes taxes & fees
Image gallery for Beach Studio with pool and summer Kitchen near Mayo, TPC
9.29.2 out of 10 rating
Wonderful
(16 reviews)
Beach Studio with pool and summer Kitchen near Mayo, TPC
Jacksonville Beach, FL
7% off
Price is NZ$3,261
NZ$3,261
NZ$466 per night
includes taxes & fees
Find spaces that suit your style
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Find the best place to stay - Mayo Clinic Florida
Kasa Southside Jacksonville
Sleeps 4 · 1 bedroom
9.29.2 out of 10
Wonderfulwonderful
24 reviews(24 reviews)
3 miles>Mayo!💫Suite Dreams@The Waterfront Oasis✨Jax Beach!
Sleeps 5 · 1 bedroom · 1 bathroom
9.09.0 out of 10
Wonderfulwonderful
53 reviews(53 reviews)
2 Cozy bedroom house W/ huge patio!
Sleeps 4 · 2 bedrooms · 1 bathroom
9.49.4 out of 10
Exceptionalexceptional
16 reviews(16 reviews)
Cute, comfy and pet friendly cottage close to everything!
Sleeps 6 · 2 bedrooms · 1 bathroom
1010 out of 10
Exceptionalexceptional
2 reviews(2 reviews)
Jax Beach home. Close to the beaches, shops, restaurants and bars.
Sleeps 4 · 2 bedrooms · 1 bathroom
9.09.0 out of 10
Wonderfulwonderful
42 reviews(42 reviews)
Whispering Woods Hideaway - Centrally Located
Sleeps 4 · 2 bedrooms · 2 bathrooms
6.06.0 out of 10
1 review(1 review)
Peace of mindOur Book with Confidence guarantee gives you 24/7 support
More quality timeFrom booking to staying, the whole process is simple and enjoyable
All the privacy of homeEnjoy full kitchens, laundry, pools, gardens and more
More for lessMore space, more privacy, more amenities — more value