Photo by Amber Palmer
Holiday rentals near Mayo Clinic Florida
We found 1,352 holiday rentals — enter your dates for availability
Discover a selection of holiday rentals within easy reach of Mayo Clinic Florida that can be your home away from home. Whether you’re travelling with friends, family or just with your pet, holiday homes have the best amenities for hanging out with the people that matter most, which might include parking and a fireplace. No matter what you're looking for, you're sure to find a property to rent that has what everyone needs, including accessible or non-smoking choices.
Holiday rentals with weekly discounts - Mayo Clinic Florida
Showing deals for:3 Oct - 10 Oct
Image gallery for TPC Sawgrass Players Club Villa - Ponte Vedra Beach.
9.89.8 out of 10 rating
Exceptional
(31 reviews)
TPC Sawgrass Players Club Villa - Ponte Vedra Beach.
Ponte Vedra Beach, FL
8% off
Price is NZ$6,393
NZ$6,393
NZ$913 per night
includes taxes & fees
Image gallery for 4 blocks from beach! spacious getaway w game room, outdoor kitchen. Kid-friendly
1010 out of 10 rating
Exceptional
(16 reviews)
4 blocks from beach! spacious getaway w game room, outdoor kitchen. Kid-friendly
Jacksonville Beach, FL
11% off
Price is NZ$7,679
NZ$7,679
NZ$1,097 per night
includes taxes & fees
Image gallery for Gorgeous POOL HOME - 5 min walk to Jax Beach!
9.09.0 out of 10 rating
Wonderful
(34 reviews)
Gorgeous POOL HOME - 5 min walk to Jax Beach!
Jacksonville Beach, Florida
8% off
Price is NZ$7,607
NZ$7,607
NZ$1,087 per night
includes taxes & fees
Image gallery for Heated Pool & Game Room! The Sunshine Cottage
1010 out of 10 rating
Exceptional
(26 reviews)
Heated Pool & Game Room! The Sunshine Cottage
Jacksonville Beach, Florida
8% off
Price is NZ$4,760
NZ$4,760
NZ$680 per night
includes taxes & fees
Image gallery for Fancy private pool home in Jax beach
9.89.8 out of 10 rating
Exceptional
(20 reviews)
Fancy private pool home in Jax beach
Jacksonville Beach, FL
8% off
Price is NZ$5,320
NZ$5,320
NZ$760 per night
includes taxes & fees
Image gallery for AquaTerra Retreat - New Heated & Cooled Pool
9.49.4 out of 10 rating
Exceptional
(25 reviews)
AquaTerra Retreat - New Heated & Cooled Pool
Jacksonville Beach, Florida
7% off
Price is NZ$12,295
NZ$12,295
NZ$1,756 per night
includes taxes & fees
Image gallery for Lux Italian house close to the beach
9.69.6 out of 10 rating
Exceptional
(10 reviews)
Lux Italian house close to the beach
Jacksonville, FL
8% off
Price is NZ$3,856
NZ$3,856
NZ$551 per night
includes taxes & fees
Image gallery for Lux Pool Home Close to Mayo & Jacksonville Beach!
1010 out of 10 rating
Exceptional
(6 reviews)
Lux Pool Home Close to Mayo & Jacksonville Beach!
Jacksonville Beach, FL
6% off
Price is NZ$4,345
NZ$4,345
NZ$621 per night
includes taxes & fees
Image gallery for Ocean Views - 3 bedroom Oasis
9.49.4 out of 10 rating
Exceptional
(8 reviews)
Ocean Views - 3 bedroom Oasis
Jacksonville Beach, FL
8% off
Price is NZ$2,855
NZ$2,855
NZ$408 per night
includes taxes & fees
Image gallery for Beautiful Townhome 2 Blocks from the beach with beach cruisers!
9.69.6 out of 10 rating
Exceptional
(7 reviews)
Beautiful Townhome 2 Blocks from the beach with beach cruisers!
Jacksonville Beach, FL
8% off
Price is NZ$3,520
NZ$3,520
NZ$503 per night
includes taxes & fees
Image gallery for 3-bedroom vacation home 14 minutes from St. Johns Town Center
9.49.4 out of 10 rating
Exceptional
(29 reviews)
3-bedroom vacation home 14 minutes from St. Johns Town Center
Ponte Vedra Beach, FL
8% off
Price is NZ$8,404
NZ$8,404
NZ$1,201 per night
includes taxes & fees
Image gallery for Jax Beach Bungalow+Hot Tub Swim Spa+Beach Access
1010 out of 10 rating
Exceptional
(44 reviews)
Jax Beach Bungalow+Hot Tub Swim Spa+Beach Access
Jacksonville Beach, FL
8% off
Price is NZ$6,713
NZ$6,713
NZ$959 per night
includes taxes & fees
Image gallery for Beach & pool in South Jax Beach sleeps 8 to 12!
9.69.6 out of 10 rating
Exceptional
(23 reviews)
Beach & pool in South Jax Beach sleeps 8 to 12!
Jacksonville Beach, FL
7% off
Price is NZ$8,580
NZ$8,580
NZ$1,226 per night
includes taxes & fees
Image gallery for Light Grey Getaway under 2 miles to mayo, 4 miles to the beach
9.49.4 out of 10 rating
Exceptional
(62 reviews)
Light Grey Getaway under 2 miles to mayo, 4 miles to the beach
Jacksonville Beach, FL
11% off
Price is NZ$3,369
NZ$3,369
NZ$481 per night
includes taxes & fees
Image gallery for Beautiful coastal condo - walk to the beach!
1010 out of 10 rating
Exceptional
(12 reviews)
Beautiful coastal condo - walk to the beach!
Neptune Beach, FL
8% off
Price is NZ$2,319
NZ$2,319
NZ$331 per night
includes taxes & fees
Image gallery for Spacious Home: Near Beach, Large Yard, Game Room & Dog-Friendly!
1010 out of 10 rating
Exceptional
(5 reviews)
Spacious Home: Near Beach, Large Yard, Game Room & Dog-Friendly!
Jacksonville, FL
11% off
Price is NZ$2,956
NZ$2,956
NZ$422 per night
includes taxes & fees
Image gallery for ~Beach Haven~ Walk to the beach!
9.69.6 out of 10 rating
Exceptional
(12 reviews)
~Beach Haven~ Walk to the beach!
Neptune Beach, FL
6% off
Price is NZ$2,886
NZ$2,886
NZ$412 per night
includes taxes & fees
Image gallery for Spacious Home w/ Pool-Tucked Away in Jax Beach!
9.89.8 out of 10 rating
Exceptional
(38 reviews)
Spacious Home w/ Pool-Tucked Away in Jax Beach!
Jacksonville Beach, Florida
8% off
Price is NZ$8,950
NZ$8,950
NZ$1,279 per night
includes taxes & fees
Image gallery for Cozy & Cheerful Oceanfront 2-bedroom condo w/ pool
1010 out of 10 rating
Exceptional
(37 reviews)
Cozy & Cheerful Oceanfront 2-bedroom condo w/ pool
Jacksonville Beach, FL
12% off
Price is NZ$3,910
NZ$3,910
NZ$559 per night
includes taxes & fees
Image gallery for Heated Pool & Putting Green! Ocean Oasis Jax Beach
1010 out of 10 rating
Exceptional
(5 reviews)
Heated Pool & Putting Green! Ocean Oasis Jax Beach
Jacksonville Beach, Florida
8% off
Price is NZ$5,981
NZ$5,981
NZ$854 per night
includes taxes & fees
Image gallery for Big Wheelchair Accessible Home Close to Beach/Mayo with Zen Den and Fenced Yard
9.89.8 out of 10 rating
Exceptional
(28 reviews)
Big Wheelchair Accessible Home Close to Beach/Mayo with Zen Den and Fenced Yard
Jacksonville Beach, FL
12% off
Price is NZ$3,949
NZ$3,949
NZ$564 per night
includes taxes & fees
Image gallery for Mayo Clinc 1mile from Intercoastal waterfront home w/pool and Breathtaking Views
9.89.8 out of 10 rating
Exceptional
(107 reviews)
Mayo Clinc 1mile from Intercoastal waterfront home w/pool and Breathtaking Views
Jacksonville Beach, FL
9% off
Price is NZ$4,344
NZ$4,344
NZ$621 per night
includes taxes & fees
Image gallery for Tides Beach Paradise best served patch of beach!
1010 out of 10 rating
Exceptional
(10 reviews)
Tides Beach Paradise best served patch of beach!
Jacksonville Beach, Florida
7% off
Price is NZ$3,611
NZ$3,611
NZ$516 per night
includes taxes & fees
Image gallery for Family Beach House with Pool - Blocks From Beach
9.49.4 out of 10 rating
Exceptional
(6 reviews)
Family Beach House with Pool - Blocks From Beach
Jacksonville Beach, Florida
8% off
Price is NZ$10,896
NZ$10,896
NZ$1,557 per night
includes taxes & fees
Find spaces that suit your style
House
Condo/Apartment
Cabin
Cottage
Villa
Chalet
Find properties near top attractions in Mayo Clinic Florida
Map Attractions
Find the best place to stay - Mayo Clinic Florida
Kasa Southside Jacksonville
Sleeps 4 · 1 bedroom
9.29.2 out of 10
Wonderfulwonderful
26 reviews(26 reviews)
Charming retreat near Downtown and the Hospitals. Short drive to the beach.
Sleeps 6 · 3 bedrooms · 1 bathroom
1010 out of 10
Exceptionalexceptional
2 reviews(2 reviews)
Charming 2-bedroom townhome in gorgeous Ponte Vedra Beach
Sleeps 5 · 2 bedrooms · 1+ bathroom
9.89.8 out of 10
Exceptionalexceptional
7 reviews(7 reviews)
Walk to the beach! Two bedroom unit in the heart of Jax Beach
Sleeps 4 · 2 bedrooms · 1 bathroom
9.89.8 out of 10
Exceptionalexceptional
11 reviews(11 reviews)
Super Cute & Cozy Home Near Everything With Fenced Back Yard, TV, A C, W/ D
Sleeps 6 · 2 bedrooms · 1 bathroom
1010 out of 10
Exceptionalexceptional
1 review(1 review)
Cozy Hideaway in Jacksonville
Sleeps 3 · 1 bedroom · 1 bathroom
9.49.4 out of 10
Exceptionalexceptional
11 reviews(11 reviews)
Peace of mindOur Book with Confidence guarantee gives you 24/7 support
More quality timeFrom booking to staying, the whole process is simple and enjoyable
All the privacy of homeEnjoy full kitchens, laundry, pools, gardens and more
More for lessMore space, more privacy, more amenities — more value