Entire home
6000SF~Sleeps24~Louisville~Views~LawnOasis~HotTub~Dome~Firepit~Pet~Lux Amenities
Photo gallery for 6000SF~Sleeps24~Louisville~Views~LawnOasis~HotTub~Dome~Firepit~Pet~Lux Amenities





Reviews
10 out of 10
Exceptional
8 bedrooms 6 bathrooms Sleeps 24 538.8 sq m
Popular amenities
Explore the area

Jeffersonville, IN
- KFC Yum Center3 min drive
- Louisville Waterfront Park4 min drive
- Kentucky International Convention Center4 min drive
- Louisville, KY (LOU-Bowman Field)12 min drive
Rooms & beds
8 bedrooms (sleeps 24)
Bedroom 1
1 King Bed
Bedroom 2
1 Queen Bed
Bedroom 3
1 King Bed
Bedroom 4
2 Queen Beds
Bedroom 5
1 King Bed
Bedroom 6
1 Queen Bed
Bedroom 7
1 King Bed
Bedroom 8
2 Queen Beds
Living Room
1 Double Sofa Bed
Living Room
1 Double Sofa Bed
6 bathrooms
Bathroom 1
Toilet · Shower only
Bathroom 2
Bathtub or shower · Toilet
Bathroom 3
Bathtub or shower · Toilet
Bathroom 4
Toilet · Shower only
Bathroom 5
Bathtub or shower · Toilet
Bathroom 6
Bathtub or shower · Toilet
Spaces
Deck or patio
Porch or lanai
Kitchen
Balcony
Outdoor play area
Garden
About this property
6000SF~Sleeps24~Louisville~Views~LawnOasis~HotTub~Dome~Firepit~Pet~Lux Amenities
*** Deaconess Guesthouse – Historic Luxury on the Ohio River, Minutes from Louisville & Jeffersonville ***
★ Where History Meets Timeless Luxury
Step into the elegance of the Deaconess Guesthouse, a fully reimagined 1800s landmark that once served as Jeffersonville’s first public hospital. Expertly restored by Charming Vacation Homes, this iconic estate seamlessly combines historic charm with boutique-style comforts. With panoramic Ohio River views and a location just minutes from downtown Louisville, the Bourbon Trail and Jeffersonville’s lively riverfront district, it offers a truly unparalleled setting for your next gathering.
★ Crafted for Groups & Celebrations
With 8 bedrooms and 6 bathrooms spread across four private units, the estate comfortably welcomes up to 24 guests. Whether hosting a family reunion, corporate retreat, wedding party or milestone celebration, the home’s layout offers the perfect blend of shared spaces and private retreats. Every detail—from the expansive living areas to the refined finishes and curated décor—is designed to create an atmosphere of warmth, connection and lasting memories.
★ Signature Features & Amenities
1. Private Hot Tub & Fire Pit – Unwind beneath the stars in your own riverfront oasis
2. Wraparound Porches & Balconies – Start mornings with sunrise views end with evening cocktails
3. Stargazing Dome – A one-of-a-kind retreat, perfect for both kids and adults
4. Ample On-Site Parking – Convenient for large groups, events and VIP transportation (concierge recommendations)
★ A Location Unlike Any Other
- Walk to Downtown Jeffersonville – Explore boutique shops, local dining, and riverfront entertainment
- Just 2.5 Miles to Downtown Louisville – Experience bourbon distilleries, Churchill Downs, world-class museums and live events
- Adventure at Your Doorstep – Enjoy kayaking, biking trails, riverfront concerts and seasonal festivals nearby
★ Your Exclusive Riverfront Escape
From tranquil mornings on the porch to evenings around the fire pit, the Deaconess Guesthouse offers a stay that is both indulgent and inspiring. Its rich history, scenic riverfront setting and luxury amenities make it an extraordinary destination for guests who expect more than just a place to stay.
★ Now Booking for Exclusive Stays & Events
Perfect for:
- Corporate retreats & executive gatherings
- Multi-family vacations
- Wedding parties & milestone celebrations
- Girls’/Guys’ getaways
- Holiday gatherings & festive weekends
Book your stay today and create memories in one of Jeffersonville’s most historic and luxurious riverfront estates.
★ CONVENIENT LOCATION
The house is centrally located and is within a 10-15 minute Uber/Lyft drive to most locations:
- Big Four Walking Bridge (Connecting KY and IN) - 0.4 miles (2 mins)
- Downtown Louisville/ 4th Street Live - 2.4 miles (6 mins)
- KFC Yum Center - 2.3 miles (7 mins)
- Churchill Downs (DERBY) - 7.7 miles (15 mins)
- Waterfront Park - 3.4 miles (9 mins)
- Papa Johns Stadium (Cardinal Stadium) - 6.4 miles (11 mins)
- Kentucky Fairgrounds - 6.5 miles (10 min)
- University of Louisville - 6.5 miles (12 mins)
- Louisville Airport - 8.6 miles (10 mins)
- Kentucky Exposition Center - 6.7 miles (11 mins)
- Kentucky Kingdom - 7.4 miles (13 mins)
- Highland Festival Grounds - 8.5 miles (12 mins)
- Louisville Mega Cavern - 10.2 miles (19 mins)
- UPS Worldport - 11.2 miles (20 mins)
- Ford LAP Plant - 10.9 miles (16 mins)
- Waverly Hills Sanatorium - 17 miles (30 mins)
- Valhalla Golf Club - 19 miles (27 mins)
PROPERTY HIGHLIGHTS
★ Exclusive Riverfront Retreat near downtown Louisville/Jeffersonville: Experience a rare architectural masterpiece where historic elegance meets modern sophistication—perfectly situated just minutes from Louisville/Jeffersonville, New Albany and Clarksville.
★ Prime Ohio Riverfront Setting: Wake up to sweeping river views and step outside to enjoy Jeffersonville’s vibrant downtown dining, boutique shopping, lively festivals, and entertainment—all just a short stroll away.
★ Historic Charm, Modern Luxury: This meticulously restored landmark offers refined interiors, elegant finishes and one-of-a-kind details that create an atmosphere of timeless comfort.
★ Scenic Views & Inviting Spaces: Savor your morning coffee or evening cocktails from covered porches and private balconies overlooking the river’s sparkling waters.
★ Designed for Comfort & Connection: With 8 beautifully appointed bedrooms and 6 designer bathrooms, the home provides light-filled, spacious interiors perfect for relaxation, entertaining and memory-making.
★ Chef-Inspired Living: Four gourmet kitchens, each with premium appliances and upscale touches, set the stage for unforgettable meals and gatherings.
★ Family & Pet Friendly: From cozy nooks and kid-friendly areas to accommodations for pets, every member of your group will feel right at home.
★ Private Outdoor Oasis: Unwind in the hot tub, gather around the fire pit, lounge under the Hyperdome or gazebo, grill outdoors and enjoy lawn games beneath the stars.
★ Entertainment for Every Occasion: Smart Roku TVs in every bedroom, indoor/outdoor games and inviting lounge spaces ensure fun and relaxation in every season.
★ Perfect for Groups & Celebrations: Ideal for reunions, retreats and extended stays—complete with 4 washer/dryer sets, parking for 8 and flexible gathering areas designed to bring people together.
★ Your Riverfront Escape Awaits: Discover the ultimate blend of history, luxury and location—an unforgettable getaway right on the banks of the Ohio River.
★ TOP 2025 UPCOMING EVENTS
-Kentucky Bourbon Festival 2025: Sep 5-7th, 2025
-Bourbon & Beyond: Sept 11-14th, 2025
-Louder than Life: Sept 18-21st, 2025
-Jack O’ Lantern Spectacular: Oct 2025
-Halloween Weekends Louisville South KOA Holiday: Oct 2025
★ OTHER 2025 UPCOMING EVENTS (Including TRADE SHOWS)
-Equipment Expo: Oct 21th to 24th, 2025
-North American International Livestock Exposition: Nov 6th to 20th, 2025
NOTE:
1) Must be 25 or older to book.
2) Please review house rules before booking. Rental Agreement & Security Hold: Guests must e-sign our rental agreement and Must submit a $500 off-platform security hold that will be collected upon signing rental agreement but it will not be placed until 2 days prior to arrival and released 7 days after departure, if no damages are reported. Please note we are API Connected to a hotel-style software called OwnerRez to safely and securely take off-platform security deposits.
3) *** STRICT CANCELLATION for DERBY/ Bourbon & Beyond ***
4) Visitors are not permitted unless you make a special request to the host and receive approval.
5) We have exterior surveillance with voice and recording capabilities of the parking area and front door. They are in place for security of guests and the home. We do NOT have interior cameras nor camera in the backyard.
6) The Dome is not recommended for use during hot summer months. We suggest enjoying the other amenities during warmer months for optimal comfort.
7) We cannot accommodate early check-ins or late check-outs for same-day turnarounds.
8) For days without same-day turnarounds, we offer early check-ins and late check-outs at the following rates: $100 for up to 2 hours, $250 for 2 to 4 hours, and a full day's rate for more than 4 hours.
9) Please note that for cancellations of bookings made on platforms other than Airbnb, a Stripe card processing fee of 3% will be deducted from the total refund.
PLEASE REVIEW THE HOUSE RULES BEFORE BOOKING. THANK YOU !!
★ Where History Meets Timeless Luxury
Step into the elegance of the Deaconess Guesthouse, a fully reimagined 1800s landmark that once served as Jeffersonville’s first public hospital. Expertly restored by Charming Vacation Homes, this iconic estate seamlessly combines historic charm with boutique-style comforts. With panoramic Ohio River views and a location just minutes from downtown Louisville, the Bourbon Trail and Jeffersonville’s lively riverfront district, it offers a truly unparalleled setting for your next gathering.
★ Crafted for Groups & Celebrations
With 8 bedrooms and 6 bathrooms spread across four private units, the estate comfortably welcomes up to 24 guests. Whether hosting a family reunion, corporate retreat, wedding party or milestone celebration, the home’s layout offers the perfect blend of shared spaces and private retreats. Every detail—from the expansive living areas to the refined finishes and curated décor—is designed to create an atmosphere of warmth, connection and lasting memories.
★ Signature Features & Amenities
1. Private Hot Tub & Fire Pit – Unwind beneath the stars in your own riverfront oasis
2. Wraparound Porches & Balconies – Start mornings with sunrise views end with evening cocktails
3. Stargazing Dome – A one-of-a-kind retreat, perfect for both kids and adults
4. Ample On-Site Parking – Convenient for large groups, events and VIP transportation (concierge recommendations)
★ A Location Unlike Any Other
- Walk to Downtown Jeffersonville – Explore boutique shops, local dining, and riverfront entertainment
- Just 2.5 Miles to Downtown Louisville – Experience bourbon distilleries, Churchill Downs, world-class museums and live events
- Adventure at Your Doorstep – Enjoy kayaking, biking trails, riverfront concerts and seasonal festivals nearby
★ Your Exclusive Riverfront Escape
From tranquil mornings on the porch to evenings around the fire pit, the Deaconess Guesthouse offers a stay that is both indulgent and inspiring. Its rich history, scenic riverfront setting and luxury amenities make it an extraordinary destination for guests who expect more than just a place to stay.
★ Now Booking for Exclusive Stays & Events
Perfect for:
- Corporate retreats & executive gatherings
- Multi-family vacations
- Wedding parties & milestone celebrations
- Girls’/Guys’ getaways
- Holiday gatherings & festive weekends
Book your stay today and create memories in one of Jeffersonville’s most historic and luxurious riverfront estates.
★ CONVENIENT LOCATION
The house is centrally located and is within a 10-15 minute Uber/Lyft drive to most locations:
- Big Four Walking Bridge (Connecting KY and IN) - 0.4 miles (2 mins)
- Downtown Louisville/ 4th Street Live - 2.4 miles (6 mins)
- KFC Yum Center - 2.3 miles (7 mins)
- Churchill Downs (DERBY) - 7.7 miles (15 mins)
- Waterfront Park - 3.4 miles (9 mins)
- Papa Johns Stadium (Cardinal Stadium) - 6.4 miles (11 mins)
- Kentucky Fairgrounds - 6.5 miles (10 min)
- University of Louisville - 6.5 miles (12 mins)
- Louisville Airport - 8.6 miles (10 mins)
- Kentucky Exposition Center - 6.7 miles (11 mins)
- Kentucky Kingdom - 7.4 miles (13 mins)
- Highland Festival Grounds - 8.5 miles (12 mins)
- Louisville Mega Cavern - 10.2 miles (19 mins)
- UPS Worldport - 11.2 miles (20 mins)
- Ford LAP Plant - 10.9 miles (16 mins)
- Waverly Hills Sanatorium - 17 miles (30 mins)
- Valhalla Golf Club - 19 miles (27 mins)
PROPERTY HIGHLIGHTS
★ Exclusive Riverfront Retreat near downtown Louisville/Jeffersonville: Experience a rare architectural masterpiece where historic elegance meets modern sophistication—perfectly situated just minutes from Louisville/Jeffersonville, New Albany and Clarksville.
★ Prime Ohio Riverfront Setting: Wake up to sweeping river views and step outside to enjoy Jeffersonville’s vibrant downtown dining, boutique shopping, lively festivals, and entertainment—all just a short stroll away.
★ Historic Charm, Modern Luxury: This meticulously restored landmark offers refined interiors, elegant finishes and one-of-a-kind details that create an atmosphere of timeless comfort.
★ Scenic Views & Inviting Spaces: Savor your morning coffee or evening cocktails from covered porches and private balconies overlooking the river’s sparkling waters.
★ Designed for Comfort & Connection: With 8 beautifully appointed bedrooms and 6 designer bathrooms, the home provides light-filled, spacious interiors perfect for relaxation, entertaining and memory-making.
★ Chef-Inspired Living: Four gourmet kitchens, each with premium appliances and upscale touches, set the stage for unforgettable meals and gatherings.
★ Family & Pet Friendly: From cozy nooks and kid-friendly areas to accommodations for pets, every member of your group will feel right at home.
★ Private Outdoor Oasis: Unwind in the hot tub, gather around the fire pit, lounge under the Hyperdome or gazebo, grill outdoors and enjoy lawn games beneath the stars.
★ Entertainment for Every Occasion: Smart Roku TVs in every bedroom, indoor/outdoor games and inviting lounge spaces ensure fun and relaxation in every season.
★ Perfect for Groups & Celebrations: Ideal for reunions, retreats and extended stays—complete with 4 washer/dryer sets, parking for 8 and flexible gathering areas designed to bring people together.
★ Your Riverfront Escape Awaits: Discover the ultimate blend of history, luxury and location—an unforgettable getaway right on the banks of the Ohio River.
★ TOP 2025 UPCOMING EVENTS
-Kentucky Bourbon Festival 2025: Sep 5-7th, 2025
-Bourbon & Beyond: Sept 11-14th, 2025
-Louder than Life: Sept 18-21st, 2025
-Jack O’ Lantern Spectacular: Oct 2025
-Halloween Weekends Louisville South KOA Holiday: Oct 2025
★ OTHER 2025 UPCOMING EVENTS (Including TRADE SHOWS)
-Equipment Expo: Oct 21th to 24th, 2025
-North American International Livestock Exposition: Nov 6th to 20th, 2025
NOTE:
1) Must be 25 or older to book.
2) Please review house rules before booking. Rental Agreement & Security Hold: Guests must e-sign our rental agreement and Must submit a $500 off-platform security hold that will be collected upon signing rental agreement but it will not be placed until 2 days prior to arrival and released 7 days after departure, if no damages are reported. Please note we are API Connected to a hotel-style software called OwnerRez to safely and securely take off-platform security deposits.
3) *** STRICT CANCELLATION for DERBY/ Bourbon & Beyond ***
4) Visitors are not permitted unless you make a special request to the host and receive approval.
5) We have exterior surveillance with voice and recording capabilities of the parking area and front door. They are in place for security of guests and the home. We do NOT have interior cameras nor camera in the backyard.
6) The Dome is not recommended for use during hot summer months. We suggest enjoying the other amenities during warmer months for optimal comfort.
7) We cannot accommodate early check-ins or late check-outs for same-day turnarounds.
8) For days without same-day turnarounds, we offer early check-ins and late check-outs at the following rates: $100 for up to 2 hours, $250 for 2 to 4 hours, and a full day's rate for more than 4 hours.
9) Please note that for cancellations of bookings made on platforms other than Airbnb, a Stripe card processing fee of 3% will be deducted from the total refund.
PLEASE REVIEW THE HOUSE RULES BEFORE BOOKING. THANK YOU !!
Add dates for prices
Amenities
Hot tub
Kitchen
Washing machine
Dryer
Pet-friendly
Free WiFi
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House Rules
Check in after 4:00 PM
Minimum age to rent: 25
Check out before 10:00 AM
Children
Children allowed: ages 0–17
Events
No events allowed
Pets
Pets allowed
Up to 2 pets 50lbs max.
Smoking
Smoking is not permitted
Important information
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
On-site parties or group events are strictly prohibited
Host has indicated that there is a carbon monoxide detector on the property
Host has indicated that there is a smoke detector on the property
Safety features at this property include a fire extinguisher, a first aid kit and a deadlock
We should mention
A car is recommended for transport to and from this property
About the area
Jeffersonville
Located in Jeffersonville, this holiday home is in the city centre and on the waterfront. KFC Yum Center and Louisville Slugger Museum are cultural highlights, and some of the area's popular attractions include Kentucky Kingdom and Louisville Zoo. Looking to enjoy an event or a game? See what's going on at L&N Federal Credit Union Stadium or Churchill Downs. Looking to get your feet wet? Kayaking, power boating and fishing adventures can be found near the property.

Jeffersonville, IN
What's nearby
- KFC Yum Center - 3 min drive - 3.1 km
- Whiskey Row - 3 min drive - 3.1 km
- Louisville Waterfront Park - 4 min drive - 3.4 km
- Kentucky International Convention Center - 4 min drive - 3.8 km
- Louisville Slugger Museum - 4 min drive - 4.5 km
Getting around
Restaurants
- Pearl Street Taphouse - 12 min walk
- H.M. Franks, an O'Shea's Pub - 10 min walk
- Harry's Taphouse & Kitchen - 6 min walk
- Cluckers - 6 min walk
- Parlour - 10 min walk
Frequently asked questions
Reviews
10
Exceptional
10/10
Cleanliness
10/10
Check-in
10/10
Communication
10/10
Location
10/10
Listing accuracy
Reviews
27 June 2025
Liked: Cleanliness, check-in, communication, location, listing accuracy
Stayed 5 nights in Jun 2025
10/10 Excellent
Cindy C.
1 July 2025
Liked: Cleanliness, check-in, communication, location, listing accuracy
Great family time
Cindy C.
Stayed 3 nights in Jun 2025
10/10 Excellent
katherine k.
15 June 2025
Liked: Cleanliness, check-in, communication, location, listing accuracy
katherine k.
Stayed 3 nights in Jun 2025
10/10 Excellent
Mike P.
12 August 2024
Liked: Cleanliness, check-in, communication, location, listing accuracy
Great spot for Louisville!
Mike P.
Stayed 2 nights in Aug 2024
10/10 Excellent
Kristen F.
11 July 2025
Liked: Cleanliness, check-in, communication, location, listing accuracy
Wedding Getaway
Kristen F.
Stayed 3 nights in Jul 2025
10/10 Excellent
Jeannine G.
17 March 2025
Liked: Cleanliness, check-in, communication, location, listing accuracy
JG
Jeannine G.
Stayed 3 nights in Mar 2025
10/10 Excellent
Amanda C.
6 April 2025
Liked: Cleanliness, check-in, communication, location, listing accuracy
Great location!
Amanda C.
Stayed 5 nights in Apr 2025
10/10 Excellent
Troy W.
4 December 2024
Liked: Cleanliness, check-in, communication, location, listing accuracy
Awesome, spacious, beautiful spot!!
Troy W.
Stayed 4 nights in Nov 2024
10/10 Excellent
Brian M.
12 September 2024
Liked: Cleanliness, check-in, communication, location, listing accuracy
Company Management Retreat
Brian M.
Stayed 2 nights in Sep 2024
10/10 Excellent
Jonathon C.
19 July 2025
Liked: Cleanliness, check-in, communication, location, listing accuracy
Large family vacation
Jonathon C.
Stayed 4 nights in Jul 2025
10/10 Excellent
derald g.
15 April 2025
Liked: Cleanliness, check-in, communication, location, listing accuracy
Care Free
derald g.
Stayed 5 nights in Apr 2025
10/10 Excellent
Tammy W.
12 December 2024
Liked: Cleanliness, check-in, communication, location, listing accuracy
Wonderful in every way!
Tammy W.
Stayed 3 nights in Dec 2024
About the host
Hosted by Kapil S Hora

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