A person paddleboarding on a calm sea with wind turbines in the background.

Santa Isabel houses

We found 52 houses — enter your dates for availability

Explore Santa Isabel house rentals

Image of Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Sleeps 9 · 4 bedrooms · 3 bathrooms

Image of Modern Cozy Home in Puerto Rican Paradise

Modern Cozy Home in Puerto Rican Paradise

Sleeps 5 · 2 bedrooms · 1 bathroom

Image of Beachfront Bliss: Spacious 5-Bedroom, 2-Bath Escape with Stunning Ocean Views

Beachfront Bliss: Spacious 5-Bedroom, 2-Bath Escape with Stunning Ocean Views

Sleeps 10 · 5 bedrooms · 2 bathrooms

Image of Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

Sleeps 10 · 4 bedrooms · 2 bathrooms

Image of 3BR Puerto Rico Villa w Pool | Aqua Bella 1

Premier Host

3BR Puerto Rico Villa w Pool | Aqua Bella 1

Sleeps 7 · 3 bedrooms · 2 bathrooms

Image of Salinas Blue House 2 in the Beach, Private Pool

Salinas Blue House 2 in the Beach, Private Pool

Sleeps 9 · 4 bedrooms · 4 bathrooms

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