Isle of Palms holiday homes

We found 685 holiday rentals — enter your dates for availability

Discover a selection of 28 homes, 10 apartments and other holiday rentals in Isle of Palms that are perfect for your trip. Holiday homes provide the amenities that you need and want for your stay with friends, family or just your pet, such as parking and a fireplace. No matter what you're looking for, you'll be able to choose a property to rent to meet everyone's needs, including a place that's non-smoking or offers accessibility.

Holiday rentals with weekly discounts - Isle of Palms

Showing deals for:16 Jan - 23 Jan
  • Peace of mind

    Our Book with Confidence guarantee gives you 24/7 support
  • More quality time

    From booking to staying, the whole process is simple and enjoyable
  • All the privacy of home

    Enjoy full kitchens, laundry, pools, gardens and more
  • More for less

    More space, more privacy, more amenities — more value

Frequently asked questions

Are there holiday rentals in Isle of Palms?
Yes, there are holiday rentals close to the most popular sights in Isle of Palms, or you can select a more secluded option if you're looking for a relaxing stay.
How many holiday rentals are there in Isle of Palms?
Choose from 28 Expedia holiday rentals in Isle of Palms for a memorable holiday.
What's there to see and do in Isle of Palms?
Explore the area and family-friendly sights such as Splash Island Water Park, or get out into nature at a spot like Tampa Bay. In the wider area, you'll find John's Pass Village & Boardwalk and St. Petersburg Municipal Beach.
What's a holiday rental in Isle of Palms like?
Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Isle of Palms. Holiday rentals feature extras like WiFi and washers and dryers so you'll feel just like you're staying in your own home. If you're concerned about a clean environment, holiday rentals can provide a sense of security away from public hotel lifts and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also find more space in a holiday rental than in a traditional hotel, which is another reason why a holiday rental is a popular option for a family getaway.