Downtown Isle of Palms holiday homes

We found 410 holiday rentals — enter your dates for availability
Select from 28 houses, 166 flats and other holiday rentals to find the perfect place for your stay in Downtown Isle of Palms. Whether you're travelling with a group or just with your pet, holiday rentals have the best amenities for spending time at your holiday home, such as Wi-Fi and cable TV. No matter what you're looking for, you'll be sure to find a property to rent for everyone's needs, including a place that's non-smoking or offers accessibility.

Holiday rentals with weekly discounts – Downtown Isle of Palms

Showing deals for:13 Nov - 20 Nov

Kitchen and dining Beach Dream, 2605 Cameron Blvd, Isle of Palms, SC | IOP Escapes
screened porch Beach Dream, 2605 Cameron Blvd, Isle of Palms, SC | IOP Escapes
kitchen island Beach Dream, 2605 Cameron Blvd, Isle of Palms, SC | IOP Escapes
Chef's Kitchen, Beach Dream, 2605 Cameron Blvd, Isle of Palms, SC | IOP Escapes
Exceptional
(18 reviews)

5 BR Luxury Home w Pool | 3 Min Walk to Beach

Isle of Palms

6% off
NZ$13,105
for 7 nights, 1 home
NZ$1,872 per night
includes taxes & fees
5 BR Luxury Home w Pool | 3 Min Walk to Beach
Dining IOP Dream | 915 Ocean Blvd | Isle of Palms SC
IOP Dream | 915 Ocean Blvd | Isle of Palms SC
Open concept living and dining IOP Dream | 915 Ocean Blvd | Isle of Palms SC
Chef Kitchen IOP Dream | 915 Ocean Blvd | Isle of Palms SC
Exceptional
(40 reviews)

6-Bedroom Luxury House with Pool, Steps to Beach

Isle of Palms

6% off
NZ$18,517
for 7 nights, 1 home
NZ$2,645 per night
includes taxes & fees
6-Bedroom Luxury House with Pool, Steps to Beach
Terrace/patio
Kitchen - WhatUp Beach! | 26 22nd Ave | Isle of Palms, SC | IOP Escapes
Kitchen - WhatUp Beach! | 26 22nd Ave | Isle of Palms, SC | IOP Escapes
Open Living Room WhatUp Beach! | 26 22nd Ave | Isle of Palms, SC | IOP Escapes
Exceptional
(11 reviews)

6 BR | 6.5 BA | Sleeps 12 | Dog-Friendly | Heated Plunge Pool | Walk to Beach

Isle of Palms

6% off
NZ$17,586
for 7 nights, 1 home
NZ$2,512 per night
includes taxes & fees
6 BR | 6.5 BA | Sleeps 12 | Dog-Friendly | Heated Plunge Pool | Walk to Beach
Aerial View of IOP Life
Large Kitchen with walk out to Pool Deck
Welcome to IOP Life at 27 22nd Avenue
Open Kitchen with Seating for the Entire Group
Exceptional
(26 reviews)

6BR 6BA Isle of Palms Vacation Rental Pet Friendly, Luxury Coastal Retreat

Isle of Palms

6% off
NZ$17,210
for 7 nights, 1 home
NZ$2,459 per night
includes taxes & fees
6BR 6BA Isle of Palms Vacation Rental Pet Friendly, Luxury Coastal Retreat
Front of House | IOP Escapes Front Beach Fun | 9 JC Long Blvd | Isle of Palms, SC
Aerial View of Home | IOP Escapes Front Beach Fun | 9 JC Long Blvd | Isle of Palms, SC
Dining and Kitchen | IOP Escapes Front Beach Fun | 9 JC Long Blvd | Isle of Palms, SC
Primary King Bedroom 1 | IOP Escapes Front Beach Fun | 9 JC Long Blvd | Isle of Palms, SC
Exceptional
(11 reviews)

6 Bedroom IOP Home w/ Community Pool Just Outside | Steps from Beach and Fun

Isle of Palms

6% off
NZ$12,814
for 7 nights, 1 home
NZ$1,831 per night
includes taxes & fees
6 Bedroom IOP Home w/ Community Pool Just Outside | Steps from Beach and Fun
An oceanfront patio for morning coffee 208 1140 Ocean Blvd, Isle of Palms, SC | IOP Escapes
1140 Ocean Blvd. welcomes guests with beautiful oceanfront views
Open-concept living and dining area 208 1140 Ocean Blvd, Isle of Palms, SC | IOP Escapes
A private boardwalk to the beach
Exceptional
(103 reviews)

Beautiful Oceanfront 4BR Condo in the Heart of IOP with Pool.

Isle of Palms

6% off
NZ$7,386
for 7 nights, 1 apartment
NZ$1,055 per night
includes taxes & fees
Beautiful Oceanfront 4BR Condo in the Heart of IOP with Pool.
Living area
Walkway with lights
Living area
Living area
Exceptional
(105 reviews)

"Cottage by the Sea"

Isle of Palms

7% off
NZ$3,870
for 7 nights, 1 home
NZ$553 per night
includes taxes & fees
"Cottage by the Sea"
Front beach IOP | Sea Gull | 201 Oceanview | 1116 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Beachfront Balcony | Sea Gull | 201 Oceanview | 1116 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Kitchen | Sea Gull | 201 Oceanview | 1116 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Oceanview | Sea Gull | 201 Oceanview | 1116 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Exceptional
(207 reviews)

3BR Oceanfront Condo; Heart of IOP

Isle of Palms

7% off
NZ$6,048
for 7 nights, 1 apartment
NZ$864 per night
includes taxes & fees
3BR Oceanfront Condo; Heart of IOP
Balcony, Pool, & Ocean
Balcony & Ocean
Owners Bedroom
1140 Ocean Blvd Complex & Ocean
Exceptional
(77 reviews)

Spectacular Ocean Front Condo 1140 OB Blvd #108 4 BR / 3 BA IOP, SC, Sleeps 12+

Isle of Palms

7% off
NZ$10,277
for 7 nights, 1 apartment
NZ$1,468 per night
includes taxes & fees
Spectacular Ocean Front Condo 1140 OB Blvd #108 4 BR / 3 BA IOP, SC, Sleeps 12+
Enjoy relaxing in the hammock or taking a refreshing shower outdoors
Well equipped kitchen with everything you need.
Master bedroom - Queen bed w/TV
Front door opens to living room.
Exceptional
(57 reviews)

Cozy Coastal Blue Crab Bungalow- Outdoor Shower- Fully Fenced Yard Isle of Palms

Isle of Palms

8% off
NZ$5,775
for 7 nights, 1 home
NZ$825 per night
includes taxes & fees
Cozy Coastal Blue Crab Bungalow- Outdoor Shower- Fully Fenced Yard Isle of Palms
Dining room
Relax on the back porch.
Wet bar and Smart tv with Roku in living room
Living area
Exceptional
(102 reviews)

Family Friendly House with Master BR on Ground Floor

Isle of Palms

7% off
NZ$3,797
for 7 nights, 1 home
NZ$542 per night
includes taxes & fees
Family Friendly House with Master BR on Ground Floor
Back porch views of the ocean | Starfish | Oceanview 101 | 1116 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Oceanview | Starfish | Oceanview 101 | 1116 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Beach Gate | Starfish | Oceanview 101 | 1116 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Marina | Starfish | Oceanview 101 | 1116 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Exceptional
(85 reviews)

Pet Friendly | 3BR First Floor Oceanfront Condo | Heart of IOP

Isle of Palms

7% off
NZ$6,285
for 7 nights, 1 apartment
NZ$898 per night
includes taxes & fees
Pet Friendly | 3BR First Floor Oceanfront Condo | Heart of IOP
Community pool | Susu's Sea Cabin | 238C 1300 Ocean Blvd | Isle of Palms, SC | IOP Escapes
Welcome to Susu's Sea Cabin | 238C 1300 Ocean Blvd | Isle of Palms, SC | IOP Escapes
Entrance to Sea Cabins | Susu's Sea Cabin | 238C 1300 Ocean Blvd | Isle of Palms, SC | IOP Escapes
Living Room | Susu's Sea Cabin | 238C 1300 Ocean Blvd | Isle of Palms, SC | IOP Escapes8C | Isle of Palms, SC | IOP Escapes
Exceptional
(13 reviews)

Oceanfront 2nd Floor Luxury Condo - Community Pool & Fishing Pier!

Isle of Palms

6% off
NZ$3,324
for 7 nights, 1 home
NZ$475 per night
includes taxes & fees
Oceanfront 2nd Floor Luxury Condo - Community Pool & Fishing Pier!
Kitchen Island | 211C Oceanside Villas | Isle of Palms SC | IOP Escapes Villa Solea
Kitchen and Island | 211C Oceanside Villas | Isle of Palms SC | IOP Escapes Villa Solea
View of Condo from Kitchen | 211C Oceanside Villas | Isle of Palms SC | IOP Escapes Villa Solea
Oceanside Villas Aerial View Near The Beach | 211C Oceanside Villas | Isle of Palms SC | IOP Escapes Villa Solea
Exceptional
(10 reviews)

Newly Renovated | 2 BR Condo w Pool | Steps to Beach w Pier Access

Isle of Palms

6% off
NZ$3,728
for 7 nights, 1 apartment
NZ$533 per night
includes taxes & fees
Newly Renovated | 2 BR Condo w Pool | Steps to Beach w Pier Access
Dining | Palms Postcard | 1006 Ocean Blvd, Dunescape 103, Isle of Palms, SC | IOP Escapes
Living Room view of beach | Palms Postcard | 1006 Ocean Blvd, Dunescape 103, Isle of Palms, SC | IOP Escapes
Front Beach IOP | Palms Postcard | 1006 Ocean Blvd, Dunescape 103, Isle of Palms, SC | IOP Escapes
Exterior Dunescape Isle of Palms, SC | IOP Escapes
Exceptional
(10 reviews)

FIrst Floor End Unit 3 BR Oceanfront Condo w/ Pool | Isle of Palms Beach Rental

Isle of Palms

7% off
NZ$7,881
for 7 nights, 1 apartment
NZ$1,126 per night
includes taxes & fees
FIrst Floor End Unit 3 BR Oceanfront Condo w/ Pool | Isle of Palms Beach Rental
Sea Cabins Northern Aerial View, Isle of Palms, SC
Sea Cabins Southern Aerial View, Isle of Palms, SC
Aerial View of Isle of Palms, SC | IOP Escapes
Sea Cabins Northern Aerial View, Isle of Palms, SC
Exceptional
(19 reviews)

1 Bedroom Oceanfront Condo Sea Cabin 230B | Pool | Renovated in 2024

Isle of Palms

6% off
NZ$3,402
for 7 nights, 1 apartment
NZ$486 per night
includes taxes & fees
1 Bedroom Oceanfront Condo Sea Cabin 230B | Pool | Renovated in 2024
Beach Gate | Sand Dollar | 102 Oceanview | 1116 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Oceanview | Sand Dollar | 102 Oceanview | 1116 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Bedroom 1: Primary King Suite | Sand Dollar | 102 Oceanview | 1116 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Beachfront Porch | Sand Dollar | 102 Oceanview | 1116 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Exceptional
(225 reviews)

Pet Friendly | 3 BR First Floor Oceanfront Condo | Heart of IOP

Isle of Palms

7% off
NZ$6,048
for 7 nights, 1 apartment
NZ$864 per night
includes taxes & fees
Pet Friendly | 3 BR First Floor Oceanfront Condo | Heart of IOP
Exterior
Ocean View from Balcony
Entry to Municipal Parking Lot
Pool
Excellent
(20 reviews)

Thrifty with WiFi and Video Streaming

Isle of Palms

7% off
NZ$2,771
for 7 nights, 1 apartment
NZ$396 per night
includes taxes & fees
Thrifty with WiFi and Video Streaming
Sleeper Sofa in Living Room | IOP Escapes The Admiral | Sea Cabins 307A | Top Floor Luxury Oceanfront Condo
Sea Cabins Condominiums on The Ocean
Sea Cabins Condominiums on The Ocean
Entrance Hallway | IOP Escapes The Admiral | Sea Cabins 307A | Top Floor Luxury Oceanfront Condo
Exceptional
(17 reviews)

1 BR Top Floor Isle of Palms Oceanfront Sea Cabin

Isle of Palms

6% off
NZ$3,391
for 7 nights, 1 apartment
NZ$484 per night
includes taxes & fees
1 BR Top Floor Isle of Palms Oceanfront Sea Cabin
Aerial view of Isle of Palms, SC | IOP Escapes
Large family room with lots of seating, ceiling fan, and balcony access. Sea Cabin 208A, Isle of Palms, SC | IOP Escapes
Aerial view of Sea Cabin Complex and Pier, Isle of Palms, SC | IOP Escapes
Sea Cabin Fishing Pier
Exceptional
(72 reviews)

Sea Cabin 208 | 1 Bedroom Oceanfront Condo | Pool | Just Renovated

Isle of Palms

6% off
NZ$3,402
for 7 nights, 1 apartment
NZ$486 per night
includes taxes & fees
Sea Cabin 208 | 1 Bedroom Oceanfront Condo | Pool | Just Renovated
View from Morgan's Creek Bar & Grill at Isle of Palms Marina
Exterior
Outdoor dining
Living area
Exceptional
(167 reviews)

Isle Of Palms Condo, half block to beach, enter with combo, private entrance.

Isle of Palms

8% off
NZ$3,679
for 7 nights, 1 apartment
NZ$526 per night
includes taxes & fees
Isle Of Palms Condo, half block to beach, enter with combo, private entrance.
Aerial View Sea Cabins Isle of Palms, SC
Living Room at Sea Cabin 214A, Isle of Palms, SC | IOP Escapes
Living Room & Kitchen at Sea Cabin 214A, Isle of Palms, SC | IOP Escapes
Kitchen at Sea Cabin 214A, Isle of Palms, SC | IOP Escapes
Exceptional
(14 reviews)

Sea Cabin 214A | Oceanfront 1 Bedroom Condo | Pool | Brand New

Isle of Palms

6% off
NZ$3,402
for 7 nights, 1 apartment
NZ$486 per night
includes taxes & fees
Sea Cabin 214A | Oceanfront 1 Bedroom Condo | Pool | Brand New
Dining Area | | | 104A Oceanside Villas | Isle of Palms SC | IOP Escapes
Living Room | | 104A Oceanside Villas | Isle of Palms SC | IOP Escapes
Hallway |104A Oceanside Villas | Isle of Palms SC | IOP Escapes
Living Room | | | 104A Oceanside Villas | Isle of Palms SC | IOP Escapes
Wonderful
(9 reviews)

Newly Renovated | 2 BR Condo w Pool | Steps to Beach w Pier Access

Isle of Palms

6% off
NZ$3,571
for 7 nights, 1 apartment
NZ$510 per night
includes taxes & fees
Newly Renovated | 2 BR Condo w Pool | Steps to Beach w Pier Access

  • Peace of mind

    Our Book with Confidence guarantee gives you 24/7 support

  • More quality time

    From booking to staying, the whole process is simple and enjoyable

  • All the privacy of home

    Enjoy full kitchens, laundry, pools, gardens and more

  • More for less

    More space, more privacy, more amenities — more value

Frequently asked questions

Can I find holiday rentals in Downtown Isle of Palms?
Yes, there are holiday rentals close to the most popular sights in Downtown Isle of Palms, or you can select a more secluded option if you're looking for a relaxing stay.
How many holiday rentals will I find in Downtown Isle of Palms?
Expedia has 28 holiday rentals for your stay in Downtown Isle of Palms.
What can I see and do in Downtown Isle of Palms?
Isle of Palms County Park and Isle of Palms Beach are a couple of lovely local spots to get outside and enjoy nature. Front Beach and Windjammer (The) are other places to visit while you're in town.
What are holiday rentals like in Downtown Isle of Palms?
Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Downtown Isle of Palms. Holiday rentals provide amenities like WiFi and washers and dryers so your stay will be comfortable. If you're concerned about a sanitised environment, holiday rentals can offer a sense of privacy away from shared hotel lifts and lobbies bustling with people while still allowing you the enjoyment of travel. You'll also find more space in a holiday rental than in a traditional hotel, which makes a holiday rental a great choice for a family trip or a small group gathering.